RS14203
RS14203 is an orally active type IV cyclic nucleotide phosphodiesterase (PDE IV) inhibitor which can induce emesis[1].
Product Specifications
CAS Number
[159925-31-2]
Product Name Alternative
PMNPQ
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/rs14203.html
Smiles
O=[N+]([O-])C1=CC=CC(C2=CC(CC3=CC=NC=C3)=CC4=C2N=CC=C4)=C1
Molecular Formula
C21H15N3O2
Molecular Weight
341.36
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Robichaud A, et al. Emesis induced by inhibitors of type IV cyclic nucleotide phosphodiesterase (PDE IV) in the ferret. Neuropharmacology. 1999 Feb;38 (2) :289-97.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PDE4
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