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RS14203

RS14203 is an orally active type IV cyclic nucleotide phosphodiesterase (PDE IV) inhibitor which can induce emesis[1].

Product Specifications

CAS Number

[159925-31-2]

Product Name Alternative

PMNPQ

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Phosphodiesterase (PDE)

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/rs14203.html

Smiles

O=[N+]([O-])C1=CC=CC(C2=CC(CC3=CC=NC=C3)=CC4=C2N=CC=C4)=C1

Molecular Formula

C21H15N3O2

Molecular Weight

341.36

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Robichaud A, et al. Emesis induced by inhibitors of type IV cyclic nucleotide phosphodiesterase (PDE IV) in the ferret. Neuropharmacology. 1999 Feb;38 (2) :289-97.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

PDE4

Curated Selection

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