Neuromedin U (Mouse)

<strong>Neuromedin U (Mouse)</strong>_x000D_ <strong>Catalog number:</strong> MDP0842_x000D_ <strong>CAS Number: </strong>935658-91-6_x000D_ <strong>Sequence: </strong>Phe-Lys-Ala-Glu-Tyr-Gln-Ser-Pro-Ser-Val-Gly-Gln-Ser-Lys-Gly-Tyr-Phe-Leu-Phe-Arg-Pro-Arg-Asn-NH2_x000D_ <strong>Amount:</strong> 500 ug_x000D_ <strong>Molecular Weight:</strong> 2706 g/mol_x000D_ <strong>Supplied as:</strong> Powder_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20°C_x000D_ <strong>WARNING:</strong> For in vitro Research Use Only. NOT for use on humans or animals._x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Cardoso V, Chesné J, Ribeiro H, García-Cassani B, Carvalho T, Bouchery T, Shah K, Barbosa-Morais NL, Harris N, Veiga-Fernandes H. Neuronal regulation of type 2 innate lymphoid cells via neuromedin U Nature. 2017 Sep 14;549(7671):277-281._x000D_ 2: Klose CSN, Mahlakõiv T, Moeller JB, Rankin LC, Flamar AL, Kabata H, Monticelli LA, Moriyama S, Putzel GG, Rakhilin N, Shen X, Kostenis E, König GM, Senda T, Carpenter D, Farber DL, Artis D. The neuropeptide neuromedin U stimulates innate lymphoid cells and type 2 inflammation Nature. 2017 Sep 14;549(7671):282-286._x000D_ 3: Jarick KJ, Topczewska PM, Jakob MO, Yano H, Arifuzzaman M, Gao X, Boulekou S, Stokic-Trtica V, Leclère PS, Preußer A, Rompe ZA, Stamm A, Tsou AM, Chu C, Heinrich FR, Guerra GM, Durek P, Ivanov A, Beule D, Helfrich S, Duerr CU, Kühl AA, Stehle C, Romagnani C, Mashreghi MF, Diefenbach A, Artis D, Klose CSN. Non-redundant functions of group 2 innate lymphoid cells Nature. 2022 Nov;611(7937):794-800._x000D_ 4: Wallrapp A, Riesenfeld SJ, Burkett PR, Abdulnour RE, Nyman J, Dionne D, Hofree M, Cuoco MS, Rodman C, Farouq D, Haas BJ, Tickle TL, Trombetta JJ, Baral P, Klose CSN, Mahlakõiv T, Artis D, Rozenblatt-Rosen O, Chiu IM, Levy BD, Kowalczyk MS, Regev A, Kuchroo VK. The neuropeptide NMU amplifies ILC2-driven allergic lung inflammation Nature. 2017 Sep 21;549(7672):351-356._x000D_ 5: Tsou AM, Yano H, Parkhurst CN, Mahlakõiv T, Chu C, Zhang W, He Z, Jarick KJ, Zhong C, Putzel GG, Hatazaki M; JRI IBD Live Cell Bank Consortium; Lorenz IC, Andrew D, Balderes P, Klose CSN, Lira SA, Artis D. Neuropeptide regulation of non-redundant ILC2 responses at barrier surfaces Nature. 2022 Nov;611(7937):787-793._x000D_ 6: Nagashima H, Mahlakõiv T, Shih HY, Davis FP, Meylan F, Huang Y, Harrison OJ, Yao C, Mikami Y, Urban JF Jr, Caron KM, Belkaid Y, Kanno Y, Artis D, O'Shea JJ. Neuropeptide CGRP Limits Group 2 Innate Lymphoid Cell Responses and Constrains Type 2 Inflammation Immunity. 2019 Oct 15;51(4):682-695.e6._x000D_ 7: Graham ES, Turnbull Y, Fotheringham P, Nilaweera K, Mercer JG, Morgan PJ, Barrett P. Neuromedin U and Neuromedin U receptor-2 expression in the mouse and rat hypothalamus: effects of nutritional status J Neurochem. 2003 Dec;87(5):1165-73._x000D_ 8: Steel JH, Van Noorden S, Ballesta J, Gibson SJ, Ghatei MA, Burrin J, Leonhardt U, Domin J, Bloom SR, Polak JM. Localization of 7B2, neuromedin B, and neuromedin U in specific cell types of rat, mouse, and human pituitary, in rat hypothalamus, and in 30 human pituitary and extrapituitary tumors Endocrinology. 1988 Jan;122(1):270-82._x000D_ 9: Teranishi H, Hayashi M, Higa R, Mori K, Miyazawa T, Hino J, Amano Y, Tozawa R, Ida T, Hanada T, Miyazato M, Hanada R, Kangawa K, Nakao K. Role of neuromedin U in accelerating of non-alcoholic steatohepatitis in mice Peptides. 2018 Jan;99:134-141._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/31647973">10: Vestlund J, Kalafateli AL, Studer E, Westberg L, Jerlhag E. Neuromedin U induces self-grooming in socially-stimulated mice Neuropharmacology. 2020 Jan 1;162:107818. </a>_x000D_ _x000D_ <strong>Products Related to Neuromedin U (Mouse) can be found at</strong> <a href="https://moleculardepot.com/product-category/Peptides/"> Peptides</a>