Vitamin D3

Vitamin D3 (Cholecalciferol; Colecalciferol) is a naturally occuring form of vitamin D. Vitamin D3 induces cell differentiation and prevents proliferation of cancer cells.

Product Specifications

CAS Number

[67-97-0]

Product Name Alternative

Cholecalciferol; Colecalciferol

UNSPSC

12352211

Hazard Statement

H300+H310, H372

Target

Bacterial; Endogenous Metabolite; VD/VDR

Type

Natural Products

Related Pathways

Anti-infection; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

Applications

Cancer-programmed cell death

Field of Research

Cancer; Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/Cholecalciferol.html

Purity

99.94

Solubility

DMSO : 10 mg/mL (ultrasonic)

Smiles

C[C@@]12[C@](CC[C@]2([H])[C@H](C)CCCC(C)C)([H])/C(CCC1)=C/C=C3C(CC[C@@H](C\3)O)=C

Molecular Formula

C27H44O

Molecular Weight

384.64

Precautions

H300+H310, H372

References & Citations

[1]Nazik Al-Hashimi, et al. Cholecalciferol|[2]Laura Bergadà, et al. Role of local bioactivation of vitamin D by CYP27A1 and CYP2R1 in the control of cell growth in normal endometrium and endometrial carcinoma. Lab Invest. 2014 Jun;94 (6) :608-22|[3]Hiroki Yoshioka, et al. Vitamin D3-induced hypercalcemia increases carbon tetrachloride-induced hepatotoxicity through elevated oxidative stress in mice. PLoS One. 2017 Apr 27;12 (4) :e0176524.