Frunexian
Frunexian (EP-7041) is a selective and potent inhibitor of coagulation factor XI/activated factor XI, targeting to factor XIa. Frunexian exhibits antithrombotic activity, with no bleeding liability in rat mesenteric arterial puncture model. Frunexian can be used in extracorporeal membrane oxygenation (ECMO) research[1].
Product Specifications
CAS Number
[1803270-60-1]
Product Name Alternative
EP-7041
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Factor XI
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/frunexian.html
Purity
97.16
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OC([C@@H](N(C1=O)C(N[C@@H](C2CCCCC2)C)=O)[C@H]1CC3=CC=NC(N)=C3)=O
Molecular Formula
C19H26N4O4
Molecular Weight
374.43
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Available Sizes
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