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Poly-L-lysine (hydrochloride)

Poly-L-lysine hydrochloride is a nonspecific attachment factor for cells useful in promoting cell adhesion to solid substrates by enhancing electrostatic interaction between negatively charged ions of the cell membrane and the culture surface. Poly-L-lysine hydrochloride is a strong-attraction regulator that promotes liquid-liquid phase separation (LLPS) at low concentrations but suppresses LLPS at high concentrations. Antibacterial cationic peptide.[1].

Product Specifications

CAS Number

26124-78-7

UNSPSC

12352211

Target

Bacterial

Type

Oligonucleotides

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/poly-l-lysine-hydrochloride.html

Solubility

H2O : 50 mg/mL (ultrasonic; warming)

Smiles

CN[C@@H](CCCC[NH3+])C(C)=O.[n].[Cl-].[n]

Molecular Formula

(C6H14N2O2.HCl) x

Molecular Weight

30000-50000

References & Citations

[1]Archishman Ghosh, et al. Three archetypical classes of macromolecular regulators of protein liquid-liquid phase separation. Proc Natl Acad Sci U S A. 2019 Sep 24;116 (39) :19474-19483.|[2]Liang Guo, et al. pH-induced structural transition during complexation and precipitation of sodium caseinate and ε-Poly-l-lysine. Int J Biol Macromol. 2020 Jul 1;154:644-653.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Oligonucleotides

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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