L-Aspartic acid-C13-1
Product Specifications
UNSPSC Description
L-Aspartic acid-13C-1 is the deuterium labeled L-Aspartic acid[1]. L-Aspartic acid is is an amino acid, shown to be a suitable proagent for colon-specific agent deliverly[2][3].
Target Antigen
Endogenous Metabolite
Type
Isotope-Labeled Compounds
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/l-aspartic-acid-c13-1.html
Solubility
10 mM in DMSO
Smiles
OC([13CH2][C@H](N)C(O)=O)=O
Molecular Weight
134.10
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]Hosoya K, et al. Blood-brain barrier produces significant efflux of L-aspartic acid but not D-aspartic acid: in vivo evidence using the brain efflux index method. J Neurochem. 1999 Sep;73(3):1206-11.|[3]Leopold CS, et al. In vivo pharmacokinetic study for the assessment of poly(L-aspartic acid) as a drug carrier for colon-specific drug delivery. J Pharmacokinet Biopharm. 1995 Aug23(4):397-406.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N0666S10/L-Aspartic-acid-C13-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N0666S10/
Clinical Information
No Development Reported
CAS Number
68261-19-8
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