Pegloxenatide
Product Specifications
UNSPSC Description
Pegloxenatide (PEX 168), polyethylene glycol loxenatide, is a long-acting glucagon-like peptide-1 receptor agonist. Pegloxenatide can be used for the research of type 2 diabetes mellitus (T2DM)[1][2].
Target Antigen
GCGR
Type
Peptides
Related Pathways
GPCR/G Protein
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/pegloxenatide.html
Purity
90.00
Solubility
10 mM in DMSO
Smiles
[PEGn-H-{D-Ala}-EGTFTSDLSKQ-{Nle}-EEEAVRLFIEWLKQGGPSSGAPPPC-NH2]
References & Citations
[1]Wang J, et al. Polyethylene glycol loxenatide (PEX168) in subjects with renal impairment: A pharmacokinetic study. Br J Clin Pharmacol. 2019 Dec;85(12):2714-2720.|[2]Li XY, et al. Effect of polyethylene Glycol Loxenatide (long-acting GLP-1RA) on lipid, glucose levels and weight in type 2 diabetes mellitus patients with obesity. Eur Rev Med Pharmacol Sci. 2022 Nov;26(21):7996-8003.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P3491/Pegloxenatide-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P3491/Pegloxenatide-SDS-MedChemExpress.pdf
Clinical Information
Phase 3
CAS Number
2420483-82-3
Available Sizes
Curated Selection
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