Pegloxenatide
Pegloxenatide (Polyethylene glycol loxenatide) is a long-acting glucagon-like peptide-1 receptor (GLP-1RA) agonist. Pegloxenatide has various activities such as lowering blood glucose, lowering blood lipids, improving body weight, anti-inflammation, promoting wound healing, protecting the liver, and protecting the heart. Pegloxenatide can be used in the research of type 2 diabetes and its multiple complications[1][2][3][4].
Product Specifications
CAS Number
[2420483-82-3]
Product Name Alternative
Polyethylene glycol loxenatide; PEX 168
UNSPSC
12352209
Target
Akt; AMPK; Apoptosis; Autophagy; GCGR; Interleukin Related; PI3K; Reactive Oxygen Species (ROS) ; Sirtuin
Type
Peptides
Related Pathways
Apoptosis; Autophagy; Cell Cycle/DNA Damage; Epigenetics; GPCR/G Protein; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; PI3K/Akt/mTOR
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease; Inflammation/Immunology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/pegloxenatide.html
Purity
90.00
Solubility
10 mM in DMSO
Smiles
[PEGn-H-{D-Ala}-EGTFTSDLSKQ-{Nle}-EEEAVRLFIEWLKQGGPSSGAPPPC-NH2]
Molecular Formula
(C2H4O) n (C2H4O) nC206H317N55O67S
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Peptides
Clinical Information
Phase 3
Available Sizes
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