AChE-IN-68
AChE-IN-68 (compound 2l) is a potent and selective AChE inhibitor, with an IC50 value of 0.040 μM. AChE-IN-68 has high blood-brain barrier permeability. AChE-IN-68 can be used for the research of neurodegenerative disorders, particularly Alzheimer’s disease[1].
Product Specifications
UNSPSC
12352005
Target
Cholinesterase (ChE)
Type
Reference compound
Related Pathways
Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ache-in-68.html
Smiles
O=[N+](C1=CC(N2N=C(C3=CSC=C3)CC2C4=CC=C(N5CCOCC5)C=C4)=CC=C1)[O-]
Molecular Formula
C23H22N4O3S
Molecular Weight
434.51
References & Citations
[1]Sever B, et al. Novel metabolic enzyme inhibitors designed through the molecular hybridization of thiazole and pyrazoline scaffolds. Arch Pharm (Weinheim) . 2021 Dec;354 (12) :e2100294.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
AChE; BChE
Frequently Asked Questions
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