Phospho-Shp1 (Tyr536) Rabbit PE Conjugate

<strong>Phospho-Shp1 (Tyr536) Rabbit PE Conjugate </strong>_x000D_ <strong>Catalog number:</strong> B2018685_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 10 ug_x000D_ <strong>Molecular Weight or Concentration:</strong> N/A_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> 2-8°C_x000D_ <strong>Keywords:</strong> Tyrosine-protein phosphatase non-receptor type 6, Hematopoietic cell protein-tyrosine phosphatase, Protein-tyrosine phosphatase 1C, PTP-1C, SH-PTP1, PTPN6, HCP, PTP1C_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Tao T, Yang X, Zheng J, Feng D, Qin Q, Shi X, Wang Q, Zhao C, Peng Z, Liu H, Jiang WG, He J. PDZK1 inhibits the development and progression of renal cell carcinoma by suppression of SHP-1 phosphorylation Oncogene. 2017 Nov 2;36(44):6119-6131._x000D_ 2: Xiao W, Ando T, Wang HY, Kawakami Y, Kawakami T. Lyn- and PLC-beta3-dependent regulation of SHP-1 phosphorylation controls Stat5 activity and myelomonocytic leukemia-like disease Blood. 2010 Dec 23;116(26):6003-13._x000D_ 3: Zhang Z, Shen K, Lu W, Cole PA. The role of C-terminal tyrosine phosphorylation in the regulation of SHP-1 explored via expressed protein ligation J Biol Chem. 2003 Feb 14;278(7):4668-74._x000D_ 4: Yang MH, Sethi G, Ravish A, Mohan AK, Pandey V, Lobie PE, Basappa S, Basappa B, Ahn KS. Discovery of imidazopyridine-pyrazoline-hybrid structure as SHP-1 agonist that suppresses phospho-STAT3 signaling in human breast cancer cells Chem Biol Interact. 2023 Dec 1;386:110780._x000D_ 5: Murray M, Butler AM, Fiala-Beer E, Su GM. Phospho-STAT5 accumulation in nuclear fractions from vitamin A-deficient rat liver FEBS Lett. 2005 Jul 4;579(17):3669-73._x000D_ 6: Su TH, Shiau CW, Jao P, Yang NJ, Tai WT, Liu CJ, Tseng TC, Yang HC, Liu CH, Huang KW, Hu TC, Huang YJ, Wu YM, Chen LJ, Chen PJ, Chen DS, Chen KF, Kao JH. Src-homology protein tyrosine phosphatase-1 agonist, SC-43, reduces liver fibrosis Sci Rep. 2017 May 11;7(1):1728._x000D_ 7: Bragadin M, Ion-Popa F, Clari G, Bordin L. SHP-1 tyrosine phosphatase in human erythrocytes Ann N Y Acad Sci. 2007 Jan;1095:193-203._x000D_ 8: Ando T, Xiao W, Gao P, Namiranian S, Matsumoto K, Tomimori Y, Hong H, Yamashita H, Kimura M, Kashiwakura J, Hata TR, Izuhara K, Gurish MF, Roers A, Rafaels NM, Barnes KC, Jamora C, Kawakami Y, Kawakami T. Critical role for mast cell Stat5 activity in skin inflammation Cell Rep. 2014 Jan 30;6(2):366-76._x000D_ 9: Su JC, Chang CH, Wu SH, Shiau CW. Novel imidazopyridine suppresses STAT3 activation by targeting SHP-1 J Enzyme Inhib Med Chem. 2018 Dec;33(1):1248-1255._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/34117816">10: Duan B, Li Y, Geng H, Ma A, Yang X. Naringenin prevents pregnancy-induced hypertension via suppression of JAK/STAT3 signalling pathway in mice Int J Clin Pract. 2021 Oct;75(10):e14509. </a>_x000D_ _x000D_ <strong>Products Related to Phospho-Shp1 (Tyr536) Rabbit PE Conjugate can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>