N-Acetyltyramine

N-Acetyltyramine is a quorum-sensing inhibitor (QSI) compound produced by V. alginolyticus M3-10. N-Acetyltyramine is capable of inhibiting the QS of C. violaceum ATCC 12472. N-acetyltyramine reverses resistance in Doxorubicin-resistant leukemia P388 cells[1][2].

Product Specifications

CAS Number

[1202-66-0]

UNSPSC

12352005

Hazard Statement

H318

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Infection

Assay Protocol

https://www.medchemexpress.com/n-acetyltyramine.html

Purity

99.67

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

OC1=CC=C(C=C1)CCNC(C)=O

Molecular Formula

C10H13NO2

Molecular Weight

179.22

Precautions

H318

References & Citations

[1]Reina JC, et al. A Quorum-Sensing Inhibitor Strain of Vibrio alginolyticus Blocks Qs-Controlled Phenotypes in Chromobacterium violaceum and Pseudomonas aeruginosa. Mar Drugs. 2019;17 (9) :494. Published 2019 Aug 24.|[2]Kunimoto S, et al. Reversal of resistance by N-acetyltyramine or N-acetyl-2-phenylethylamine in doxorubicin-resistant leukemia P388 cells. J Antibiot (Tokyo) . 1987;40 (11) :1651-1652.