BYK 191023 (dihydrochloride)

BYK 191023 is a highly selective inducible nitric-oxide synthase (iNOS) inhibitor. BYK 191023 interacts with the catalytic center of the enzyme. BYK 191023 can be used to study the in vivo and in vitro effects mediated by iNOS [1].

Product Specifications

CAS Number

[1216722-25-6]

UNSPSC

12352005

Target

NO Synthase

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/byk-191023-dihydrochloride.html

Purity

99.63

Solubility

DMSO : 250 mg/mL (ultrasonic)

Smiles

COC1=CC=NC(CCC2=NC3=NC=CC=C3N2)=C1.Cl.Cl

Molecular Formula

C14H16Cl2N4O

Molecular Weight

327.21

References & Citations

[1]Tiso M, et al. BYK191023 (2-[2- (4-methoxy-pyridin-2-yl) -ethyl]-3h-imidazo[4,5-b]pyridine) is an NADPH- and time-dependent irreversible inhibitor of inducible nitric-oxide synthase. Mol Pharmacol. 2008 Apr;73 (4) :1244-53.