L321-NH-C3-PEG3-C1-NH2
Product Specifications
UNSPSC Description
L321-NH-C3-PEG3-C1-NH2 (CRBN ligand L321 (HY-169359)) is an E3 Ligase Ligand-Linker Conjugate for BRD4 PROTAC L134 (HY-169358)[1].
Target Antigen
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/l321-nh-c3-peg3-c1-nh2.html
Smiles
CC1=CC=C(C(/C=C2C(NC3=C\2C=CC(C(F)(F)F)=C3)=O)=C1)OCC(NCCCOCCOCCOCCCN)=O
Molecular Weight
579.61
References & Citations
[1]Man Zhao, et al. Design, Synthesis, and Activity Evaluation of BRD4 PROTAC Based on Alkenyl Oxindole-DCAF11 Pair. J Med Chem. 2024 Nov 14;67(21):19428-19447.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-169401/L321-NH-C3-PEG3-C1-NH2-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-169401/
Clinical Information
No Development Reported
Curated Selection
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