L321-NH-C3-PEG3-C1-NH2

L321-NH-C3-PEG3-C1-NH2 (CRBN ligand L321 (HY-169359) ) is an E3 Ligase Ligand-Linker Conjugate for BRD4 PROTAC L134 (HY-169358) [1].

Product Specifications

UNSPSC

12352005

Target

E3 Ligase Ligand-Linker Conjugates

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/l321-nh-c3-peg3-c1-nh2.html

Smiles

CC1=CC=C(C(/C=C2C(NC3=C\2C=CC(C(F)(F)F)=C3)=O)=C1)OCC(NCCCOCCOCCOCCCN)=O

Molecular Formula

C29H36F3N3O6

Molecular Weight

579.61

References & Citations

[1]Man Zhao, et al. Design, Synthesis, and Activity Evaluation of BRD4 PROTAC Based on Alkenyl Oxindole-DCAF11 Pair. J Med Chem. 2024 Nov 14;67 (21) :19428-19447.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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