L321-NH-C3-PEG3-C1-NH2
L321-NH-C3-PEG3-C1-NH2 (CRBN ligand L321 (HY-169359) ) is an E3 Ligase Ligand-Linker Conjugate for BRD4 PROTAC L134 (HY-169358) [1].
Product Specifications
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/l321-nh-c3-peg3-c1-nh2.html
Smiles
CC1=CC=C(C(/C=C2C(NC3=C\2C=CC(C(F)(F)F)=C3)=O)=C1)OCC(NCCCOCCOCCOCCCN)=O
Molecular Formula
C29H36F3N3O6
Molecular Weight
579.61
References & Citations
[1]Man Zhao, et al. Design, Synthesis, and Activity Evaluation of BRD4 PROTAC Based on Alkenyl Oxindole-DCAF11 Pair. J Med Chem. 2024 Nov 14;67 (21) :19428-19447.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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