KR-12 (human)

KR-12 (human) is an active segment of LL-37 (HY-P4744) . KR-12 (human) exhibits antimicrobial activity against gram-negative bacteria. KR-12 (human) inhibits E. coli K-12 with a MIC of 66 μM. KR-12 human can be used for the research of infection, such as E. coli infection[1].

Product Specifications

CAS Number

[1218951-51-9]

UNSPSC

12352209

Target

Bacterial

Type

Peptides

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/kr-12-human.html

Purity

99.91

Solubility

H2O : ≥ 100 mg/mL

Smiles

NCCCC[C@H](N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](C(C)C)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCCCN)C(N[C@@H](CC(O)=O)C(N[C@H](C(N[C@@H](CC(C)C)C(N[C@H](C(N)=O)CCCNC(N)=N)=O)=O)CC1=CC=CC=C1)=O)=O)=O)=O)=O)=O)=O)=O)=O

Molecular Formula

C71H127N25O15

Molecular Weight

1570.93

References & Citations

[1]Epand RF, et al., Lipid segregation explains selective toxicity of a series of fragments derived from the human cathelicidin LL-37. Antimicrob Agents Chemother. 2009 Sep;53 (9) :3705-14.