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Anti-Mouse IL-18 Antibody (YIGIF74-1G7)

Selected Variant

HY-P990220-01

Size: 1 mg

Anti-Mouse IL-18 Antibody (YIGIF74-1G7) is a rat-derived IgG2a κ type antibody inhibitor, targeting to mouse IL-18. Anti-Mouse IL-18 Antibody (YIGIF74-1G7) can neutralize IL-18. Anti-Mouse IL-18 Antibody (YIGIF74-1G7) can be used for the researches of cancer, infection, inflammation and immunology, such as hepatocellular carcinoma and eosinophilic esophagitis[1][2][3].

Product Specifications

CAS Number

9007-83-4

UNSPSC

12352203

Target

Interleukin Related

Type

Inhibitory Antibodies

Related Pathways

Immunology/Inflammation

Field of Research

Cancer; Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/anti-mouse-il-18-antibody-yigif74-1g7.html

Purity

97.12

Solubility

10 mM in DMSO

Smiles

[Anti-MouseIL-18Antibody(YIGIF74-1G7)]

Molecular Weight

(150 kDa)

References & Citations

[1]Goulet DR, Atkins WM. Considerations for the Design of Antibody-Based Therapeutics. J Pharm Sci. 2020 Jan;109 (1) :74-103.|[2]Molgora M, et al. IL-1R8 is a checkpoint in NK cells regulating anti-tumour and anti-viral activity. Nature. 2017 Nov 2;551 (7678) :110-114.|[3]Chudnovskiy A, et al. Host-Protozoan Interactions Protect from Mucosal Infections through Activation of the Inflammasome. Cell. 2016 Oct 6;167 (2) :444-456.e14.|[4]Yadavalli CS, et al. Allergen-induced NLRP3/caspase1/IL-18 signaling initiate eosinophilic esophagitis and respective inhibitors protect disease pathogenesis. Commun Biol. 2023 Jul 31;6 (1) :763.

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4°C for 2 years, do not freeze

Scientific Category

Inhibitory Antibodies

Clinical Information

No Development Reported

Available Sizes

Price

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