RIPK1-IN-24
RIPK1-IN-24 is a receptor-interacting protein kinase 1 (RIPK1) inhibitor with an IC50 value of 1.3 μM. RIPK1-IN-24 can be used for research on inflammatory diseases[1].
Product Specifications
CAS Number
[1358585-26-8]
UNSPSC
12352211
Target
RIP kinase
Type
Reference compound
Related Pathways
Apoptosis
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ripk1-in-24.html
Smiles
O=C(NC1=CC=C(CN2C=NC(C3=NC(C4=CC=CC(F)=C4)=NO3)=C2)C=C1)NCC5=CC=CC=C5
Molecular Formula
C26H21FN6O2
Molecular Weight
468.48
References & Citations
[1]Yu Y, et al. Discovery of 5- (1-benzyl-1H-imidazol-4-yl) -1,2,4-oxadiazole derivatives as novel RIPK1 inhibitors via structure-based virtual screening. Drug Dev Res. 2024 Aug;85 (5) :e22235.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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