RIPK1-IN-24

RIPK1-IN-24 is a receptor-interacting protein kinase 1 (RIPK1) inhibitor with an IC50 value of 1.3 μM. RIPK1-IN-24 can be used for research on inflammatory diseases[1].

Product Specifications

CAS Number

[1358585-26-8]

UNSPSC

12352211

Target

RIP kinase

Type

Reference compound

Related Pathways

Apoptosis

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/ripk1-in-24.html

Smiles

O=C(NC1=CC=C(CN2C=NC(C3=NC(C4=CC=CC(F)=C4)=NO3)=C2)C=C1)NCC5=CC=CC=C5

Molecular Formula

C26H21FN6O2

Molecular Weight

468.48

References & Citations

[1]Yu Y, et al. Discovery of 5- (1-benzyl-1H-imidazol-4-yl) -1,2,4-oxadiazole derivatives as novel RIPK1 inhibitors via structure-based virtual screening. Drug Dev Res. 2024 Aug;85 (5) :e22235.