Acetylcholine (chloride) (Standard)

Acetylcholine (chloride) (Standard) is the analytical standard of Acetylcholine (chloride) . This product is intended for research and analytical applications. Acetylcholine chloride (ACh chloride), a neurotransmitter, is a potent cholinergic agonist. Acetylcholine chloride is a modulator of the activity of dopaminergic (DAergic) neurons through the stimulation of nicotinic acetylcholine receptors (nAChRs) [1][2]. Acetylcholine chloride inhibits p53 mutant peptide aggregation in vitro[5].

Product Specifications

CAS Number

[60-31-1]

Product Name Alternative

ACh (chloride) (Standard)

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Calcium Channel; Endogenous Metabolite; nAChR; Reference Standards

Type

Reference Standards

Related Pathways

Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling; Others

Applications

Cancer-programmed cell death

Field of Research

Neurological Disease; Cancer

Assay Protocol

https://www.medchemexpress.com/acetylcholine-chloride-standard.html

Smiles

O=C(OCC[N+](C)(C)C)C.[Cl-]

Molecular Formula

C7H16ClNO2

Molecular Weight

181.66

Precautions

H302, H315, H319, H335

References & Citations

[1]Prashant Tiwari, et al. Basic and modern concepts on cholinergic receptor: A review. Asian Pac J Trop Dis. 2013 Oct;3 (5) : 413-420.|[2]A Young, et al. Diarrhoea of famine and malnutrition--investigations using a rat model. 2--Ileal hypersecretion induced by starvation. Gut. 1990 Feb;31 (2) :162-9.|[3]Xia Lei, et al. Effects of acetylcholine chloride on intracellular calcium concentration of cultured sweat gland epithelial cells. Arch Dermatol Res. 2008 Aug;300 (7) :335-41.|[4]P F Zabrodskii, et al. Effect of acetylcholine on mortality of mice from sepsis and proinflammatory cytokine production. Bull Exp Biol Med. 2011 Jan;150 (3) :340-2.|[5]Zhaolin Chen, et al. Inhibition of p53 Mutant Peptide Aggregation In Vitro by Cationic Osmolyte Acetylcholine Chloride. Protein Pept Lett. 2017;24 (4) :353-357.