8-Br-2'-O-Me-cAMP
8-Br-2'-O-Me-cAMP is an analogue of the signal molecule cyclic AMP (cAMP) . 8-Br-2'-O-Me-cAMP is an agonist of exchange factors activated by cAMP (Epac), while it doesn't activate PKA as cAMP do. 8-Br-2'-O-Me-cAMP can be used in cardiovascular disease research[1].
Product Specifications
CAS Number
612513-13-0
UNSPSC
12352005
Target
Ras
Type
Reference compound
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/8-br-2-o-me-camp.html
Smiles
NC1=NC=NC2=C1N=C(Br)N2[C@@H]3O[C@H](CO4)[C@@H](OP4(O)=O)[C@H]3OC
Molecular Formula
C11H13BrN5O6P
Molecular Weight
422.13
References & Citations
[1]Börner S, et al. FRET measurements of intracellular cAMP concentrations and cAMP analog permeability in intact cells. Nat Protoc. 2011 Apr;6 (4) :427-38.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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