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8-Br-2'-O-Me-cAMP

8-Br-2'-O-Me-cAMP is an analogue of the signal molecule cyclic AMP (cAMP) . 8-Br-2'-O-Me-cAMP is an agonist of exchange factors activated by cAMP (Epac), while it doesn't activate PKA as cAMP do. 8-Br-2'-O-Me-cAMP can be used in cardiovascular disease research[1].

Product Specifications

CAS Number

612513-13-0

UNSPSC

12352005

Target

Ras

Type

Reference compound

Related Pathways

GPCR/G Protein; MAPK/ERK Pathway

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/8-br-2-o-me-camp.html

Smiles

NC1=NC=NC2=C1N=C(Br)N2[C@@H]3O[C@H](CO4)[C@@H](OP4(O)=O)[C@H]3OC

Molecular Formula

C11H13BrN5O6P

Molecular Weight

422.13

References & Citations

[1]Börner S, et al. FRET measurements of intracellular cAMP concentrations and cAMP analog permeability in intact cells. Nat Protoc. 2011 Apr;6 (4) :427-38.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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