TGFBR1-IN-2
TGFBR1-IN-2 (Compound AQA) is a TGFBR1 inhibitor and an antibacterial agent. TGFBR1-IN-2 is a substrate for cytochrome P450s. TGFBR1-IN-2 contains the pyridyl-6-methyl moiety necessary for Mycobacterium tuberculosis inhibition and has potent inhibitory activity against non-replicating and persistent Mycobacterium tuberculosis[1].
Product Specifications
CAS Number
[733806-89-8]
UNSPSC
12352005
Target
Bacterial; Cytochrome P450; TGF-β Receptor
Type
Reference compound
Related Pathways
Anti-infection; Metabolic Enzyme/Protease; TGF-beta/Smad
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/tgfbr1-in-2.html
Purity
98.88
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC1=NC(C2=NC(NC3=CC=NC=C3)=C4C=CC=CC4=N2)=CC=C1
Molecular Formula
C19H15N5
Molecular Weight
313.36
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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