DCAP
DCAP is a broad-spectrum antibiotic targeting the membranes of both Gram-positive and Gram-negative bacteria. DCAP blocks autophagy at the late stages by preventing autophagolysosome maturation and interrupting the autophagic flux[1].
Product Specifications
CAS Number
[500015-20-3]
Product Name Alternative
VU0607402
UNSPSC
12352005
Target
Antibiotic; Autophagy; Bacterial
Type
Reference compound
Related Pathways
Anti-infection; Autophagy
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/dcap.html
Purity
99.0
Solubility
10 mM in DMSO|DMSO : ≥ 5mg/mL
Smiles
OCC(CO)(NCC(O)CN1C2=C(C3=C1C=CC(Cl)=C3)C=C(Cl)C=C2)CO
Molecular Formula
C19H22Cl2N2O4
Molecular Weight
413.29
References & Citations
[1]Giulia Allavena, et al. A broad-spectrum antibiotic, DCAP, reduces uropathogenic Escherichia coli infection and enhances vorinostat anticancer activity by modulating autophagy. Cell Death Dis. 2018 Jul 13;9 (7) :780.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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