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PAR-2 antagonist 1

PAR-2 antagonist 1 (Compound 9a) is a protease-activated receptor 2 (PAR2) antagonist with an IC50 value of 0.9 μM. PAR-2 antagonist 1 can effectively inhibit the proliferation and migration of breast cancer cells[1].

Product Specifications

CAS Number

313957-41-4

UNSPSC

12352211

Target

Protease Activated Receptor (PAR)

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/par-2-antagonist-1.html

Smiles

O=C(N/C(C(NCC1=CC=CC=C1)=O)=C\C2=CC=CC3=C2C=CC=C3)C4=CC=CC=C4

Molecular Formula

C27H22N2O2

Molecular Weight

406.48

References & Citations

[1]Kim T, et al. Discovery of Protease-activated receptor 2 antagonists derived from phenylalanine for the treatment of breast cancer. Bioorg Chem. 2024 Sep;150:107496.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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