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Anti-Mouse/Human CD11b Antibody (M1/70)

Anti-Mouse/Human CD11b Antibody (M1/70) is an anti-mouse CD11b IgG2b monoclonal antibody. Anti-Mouse/Human CD11b Antibody (M1/70) can significantly inhibit the adhesion between dendritic cells (DCs) and platelets. Anti-Mouse/Human CD11b Antibody (M1/70) can kill ovarian cancer cells and inhibit their migration. Anti-Mouse/Human CD11b Antibody (M1/70) can alleviate renal fibrosis and inflammation. Anti-Mouse/Human CD11b Antibody (M1/70) can be used for researches on inflammation conditions and cancer such as ischemia-reperfusion injury (IRI), thrombotic inflammatory conditions and ovarian cancer[1][2][3].

Product Specifications

CAS Number

9007-83-4

UNSPSC

12352203

Target

Integrin

Type

Inhibitory Antibodies

Related Pathways

Cytoskeleton

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/anti-mouse-cd11b-antibody-m1-70.html

Purity

95.00

Solubility

H2O

Smiles

[Anti-Mouse/HumanCD11bAntibody(M1/70)]

Molecular Weight

(150 kDa)

References & Citations

[1]Zhou H, et al. CD11b deficiency attenuates the ischemia/reperfusion-induced AKI-to-CKD process by regulating macrophage polarization. FASEB J. 2024 Dec 15;38 (23) :e70216.|[2]Nording H, et al. Activated Platelets Upregulate β2 Integrin Mac-1 (CD11b/CD18) on Dendritic Cells, Which Mediates Heterotypic Cell-Cell Interaction. J Immunol. 2022 Apr 1;208 (7) :1729-1741.|[3]Saed GM, et al. Novel expression of CD11b in epithelial ovarian cancer: Potential therapeutic target. Gynecol Oncol. 2018 Mar;148 (3) :567-575.

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4°C, do not freeze

Scientific Category

Inhibitory Antibodies

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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