Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Guanine

Guanine is one of the fundamental components of nucleic acids (DNA and RNA) . Guanine is a purine derivative, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds. Guanine has the potential to serve as a large-capacity N pool. Guanine has cytotoxic, antinociceptive and neuroprotective effects[1][2][3][4].

Product Specifications

CAS Number

73-40-5

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

DNA/RNA Synthesis; Endogenous Metabolite

Type

Natural Products

Related Pathways

Cell Cycle/DNA Damage; Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/Guanine.html

Purity

98.0

Solubility

DMSO : 0.15 mg/mL (ultrasonic; warming) |H2O : < 0.1 mg/mL

Smiles

O=C1N=C(N)NC2=C1NC=N2

Molecular Formula

C5H5N5O

Molecular Weight

151.13

Precautions

H315, H319, H335

References & Citations

[1]Mojzeš P, et al. Guanine, a high-capacity and rapid-turnover nitrogen reserve in microalgal cells. Proc Natl Acad Sci U S A. 2020 Dec 22;117 (51) :32722-32730. |[2]Chauhan V, et al. In Silico Discovery and Validation of Amide Based Small Molecule Targeting the Enzymatic Site of Shiga Toxin. J Med Chem. 2016 Dec 8;59 (23) :10763-10773. |[3]Messina E, et al. Guanine nucleotide depletion triggers cell cycle arrest and apoptosis in human neuroblastoma cell lines. Int J Cancer. 2004 Mar 1;108 (6) :812-7.|[4]de Oliveira ED, et al. Mechanisms involved in the antinociception induced by spinal administration of inosine or guanine in mice. Eur J Pharmacol. 2016 Feb 5;772:71-82.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Natural Products

Clinical Information

Phase 3

Isoform

Human Endogenous Metabolite; Microbial Metabolite

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

GRB2 (Ab-159) Antibody
8B8241-AAT 50 µg

GRB2 (Ab-159) Antibody

Sign In for Pricing
View Details
P63 (Squamous, Basal and Myoepithelial Cell Marker) (TP63/1786), 1mg/mL
BNUM1786-50 1x 50 µL

P63 (Squamous, Basal and Myoepithelial Cell Marker) (TP63/1786), 1mg/mL

Sign In for Pricing
View Details
Recombinant Human IL1R1/CD121a Protein (Fc Tag)
PKSH031849 100 µg

Recombinant Human IL1R1/CD121a Protein (Fc Tag)

Sign In for Pricing
View Details
PE Anti-Mouse CD41 Antibody[MWReg30]
E-AB-F1183D-01 50 Tests

PE Anti-Mouse CD41 Antibody[MWReg30]

Sign In for Pricing
View Details
PE Anti-Mouse CD41 Antibody[MWReg30]
E-AB-F1183D-02 100 Tests

PE Anti-Mouse CD41 Antibody[MWReg30]

Sign In for Pricing
View Details
PE Anti-Mouse CD41 Antibody[MWReg30]
E-AB-F1183D-03 2x 100 Tests

PE Anti-Mouse CD41 Antibody[MWReg30]

Sign In for Pricing
View Details