11-Aminoundecanoic acid
11-Aminoundecanoic acid is an alkyl chain based PROTAC linker can be used in the synthesis of PROTACs.
Product Specifications
CAS Number
[2432-99-7]
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/11-aminoundecanoic-acid.html
Purity
97.0
Solubility
DMSO : 3.33 mg/mL (ultrasonic; adjust pH to 2 with HCl) |H2O : < 0.1 mg/mL (ultrasonic; adjust pH to 3 with HCl)
Smiles
NCCCCCCCCCCC(O)=O
Molecular Formula
C11H23NO2
Molecular Weight
201.31
Precautions
H302, H315, H319, H335
References & Citations
[1]Pillow TH, et al. Antibody Conjugation of a Chimeric BET Degrader Enables in vivo Activity. ChemMedChem. 2019 Oct 31.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature 3 years
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Alkyl-Chain Linkers
Available Sizes
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NFkB, p50, p105, phosphorylated (Ser337) (Nuclear Factor kappa B p50 Subunit, Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B cells 1, NFkB1, DKFZp686C01211, DNA Binding Factor KBF1, EBP-1, KBF1, MGC54151, NF-kappa-B, Nuclear Factor kappa B D