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Tricosanoic acid

Tricosanoic acid is an endogenous agonist of long-chain saturated fatty acids and free fatty acid receptor FFAR1, which can activate hair growth. Tricosanoic acid (C23:0) has the activity of improving cognitive function by regulating neuronal membrane fluidity, inhibiting neuroinflammatory response, participating in myelination and neuronal energy metabolism. Tricosanoic acid expression levels are low in the prefrontal cortex of Alzheimer's disease (AD) models; while better cognitive performance corresponds to higher serum concentration levels. Tricosanoic acid can be used as a biomarker for diseases related to cognitive decline[1].

Product Specifications

CAS Number

[2433-96-7]

UNSPSC

12352211

Hazard Statement

H315, H319, H335

Target

Free Fatty Acid Receptor

Type

Natural Products

Related Pathways

GPCR/G Protein

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/Tricosanoic_acid.html

Purity

99.96

Solubility

Ethanol : 1 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

CCCCCCCCCCCCCCCCCCCCCCC(O)=O

Molecular Formula

C23H46O2

Molecular Weight

354.62

Precautions

H315, H319, H335

References & Citations

[1]Yang T, et al. Association between serum tricosanoic acid and cognitive function in older adults: findings from the NHANES and GEO databases. Front Aging Neurosci. 2025 Mar 20;17:1534303.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Natural Products

Clinical Information

No Development Reported

Isoform

Human Endogenous Metabolite

Available Sizes

Curated Selection

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