5-Aminolevulinic acid

5-Aminolevulinic acid (5-ALA) is a non-protein amino acid that plays a rate-limiting role in heme biosynthesis.

Product Specifications

CAS Number

[106-60-5]

Product Name Alternative

5-ALA; δ-Aminolevulinic acid; 5-Amino-4-oxopentanoic acid

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease; Cancer

Assay Protocol

https://www.medchemexpress.com/5-Amino-4-oxopentanoic_acid.html

Purity

99.92

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C(O)CCC(CN)=O

Molecular Formula

C5H9NO3

Molecular Weight

131.13

Precautions

H302, H315, H319, H335

References & Citations

[1]Pedrosa-Gerasmio IR, et al. Effects of 5-Aminolevulinic Acid on Gene Expression, Immunity, and ATP Levels in Pacific White Shrimp, Litopenaeus vannamei. Mar Biotechnol (NY) . 2018 Aug 25.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Natural Products

Clinical Information

Launched

Isoform

Human Endogenous Metabolite

Citation 01

BioRxiv. 2024 Apr 3:2023.06.02.542933.|J Inorg Biochem. 2023 Oct:247:112340.|Lasers Med Sci. 2021 Dec;36 (9) :1873-1881.|Nature. 2025 Jul;643 (8070) :192-200.|Pharmacol Res. 2021 Aug:170:105701.|PLoS Biol. 2024 Jun 27;22 (6) :e3002672.|Adv Sci (Weinh) . 2019 Jan 20;6 (5) :1802057. |Asian J Androl. 2025 Jul 1;27 (4) :454-463.|Cell Death Dis. 2021 Oct 25;12 (11) :999.|EMBO Mol Med. 2023 Mar 8;15 (3) :e16959.|Genome Biol. 2022 Dec 15;23 (1) :259.|Mar Drugs. 2025 Mar 28;23 (4) :146.|Photodiagnosis Photodyn Ther. 2022 Dec:40:103053.|Photodiagnosis Photodyn Ther. 2023 Jun:42:103612.|Photodiagnosis Photodyn Ther. 2024 Jun:47:104093.|Photodiagnosis Photodyn Ther. 2025 Apr 19:104599.|Photodiagnosis Photodyn Ther. 2025 Aug:54:104726.