Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

GSK2850163 (hydrochloride)

GSK2850163 hydrochloride is a novel inhibitor of inositol-requiring enzyme-1 alpha (IRE1α) which can inhibit IRE1α kinase activity and RNase activity with IC50s of 20 and 200 nM, respectively.

Product Specifications

CAS Number

2319838-09-8

UNSPSC

12352005

Target

IRE1

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/GSK2850163_hydrochloride.html

Solubility

10 mM in DMSO

Smiles

O=C(N(CCC1)C[C@]21CCN(CC3=CC=C(Cl)C(Cl)=C3)C2)NCC4=CC=C(C)C=C4.Cl

Molecular Formula

C24H30Cl3N3O

Molecular Weight

482.87

References & Citations

[1]Nestor O. Concha, et al. Long-Range Inhibitor-Induced Conformational Regulation of Human IRE1α Endoribonuclease Activity. Molecular Pharmacology December 2015, 88 (6) 1011-1023.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

POLA2 Mouse Monoclonal Antibody [Clone ID: OTI3G7]
CF807637 100 µg

POLA2 Mouse Monoclonal Antibody [Clone ID: OTI3G7]

Sign In for Pricing
View Details
Tissue FFPE Sections, Seminal vesicle
CS700020 5x 5 µm

Tissue FFPE Sections, Seminal vesicle

Sign In for Pricing
View Details
CPA2 Antibody
KC-7655-01 50 μL

CPA2 Antibody

Sign In for Pricing
View Details
CPA2 Antibody
KC-7655-02 100 µL

CPA2 Antibody

Sign In for Pricing
View Details
CPA2 Antibody
KC-7655-03 1 mL

CPA2 Antibody

Sign In for Pricing
View Details
10-O-Acetyl SN-38
TRC-A187735-5MG 5 mg

10-O-Acetyl SN-38

Sign In for Pricing
View Details