S-MTC
S-MTC is a selective type I nitric oxide synthase (NOS) inhibitor.
Product Specifications
CAS Number
[156719-41-4]
Product Name Alternative
S-Methyl-L-thiocitrulline
UNSPSC
12352211
Hazard Statement
H302-H315-H319-H335
Target
NO Synthase
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/S-MTC.html
Solubility
10 mM in DMSO
Smiles
N[C@@H](CCCNC(SC)=N)C(O)=O
Molecular Formula
C7H15N3O2S
Molecular Weight
205.28
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Law A, et al. Neuroprotective and neurorescuing effects of isoform-specific nitric oxide synthase inhibitors, nitric oxide scavenger, and antioxidant against beta-amyloid toxicity. Br J Pharmacol. 2001 Aug;133 (7) :1114-24.|[2]Zelinski LM, et al. A prolonged nitric oxide-dependent, opioid-mediated antinociceptive effect of hyperbaric oxygenin mice. J Pain. 2009 Feb;10 (2) :167-72.|[3]Wakefield ID, et al. Comparative regional haemodynamic effects of the nitric oxide synthase inhibitors, S-methyl-L-thiocitrulline and L-NAME, in conscious rats. Br J Pharmacol. 2003 Jul;139 (6) :1235-43.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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