What is the catalog number for MGAT2-IN-2?

The catalog number for MGAT2-IN-2 is HY-U00430.

What sizes are available for MGAT2-IN-2?

MGAT2-IN-2 is available in the following size(s): 1 Each.

Is MGAT2-IN-2 in stock?

MGAT2-IN-2 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures MGAT2-IN-2?

MGAT2-IN-2 is manufactured by QuantiMol.

What is the estimated delivery time for MGAT2-IN-2?

Estimated delivery time for MGAT2-IN-2 is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for MGAT2-IN-2?

The safety data sheet for MGAT2-IN-2 is available here: http://file.medchemexpress.com/batch_PDF/HY-U00430/.

MGAT2-IN-2

MGAT2-IN-2 is a potent and selective acyl CoA:monoacylglycerol acyltransferase 2 (MGAT2) inhibitor with an IC50 of 3.4 nM.

Product Specifications

CAS Number

1710630-11-7

UNSPSC

12352005

Target

Acyltransferase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/MGAT2-IN-2.html

Solubility

10 mM in DMSO

Smiles

O=C(N1CCC2=C1C(N3C(CCC3)=O)=CC(S(=O)(NC4=CC=C(F)C=C4F)=O)=C2)NC5=CC=C(C(F)(F)F)C=C5

Molecular Formula

C26H21F5N4O4S

Molecular Weight

580.53

References & Citations

[1]Sato K, et al. Discovery of a Novel Series of N-Phenylindoline-5-sulfonamide Derivatives as Potent, Selective, and Orally Bioavailable Acyl CoA:Monoacylglycerol Acyltransferase-2 Inhibitors. J Med Chem. 2015 May 14;58 (9) :3892-909.|[2]Sato K, et al. Optimization of a novel series of N-phenylindoline-5-sulfonamide-based acylCoA:monoacylglycerol acyltransferase-2 inhibitors: Mitigation of CYP3A4 time-dependent inhibition and phototoxic liabilities. Bioorg Med Chem. 2015 Aug 1;23 (15) :4544-60.