BTM-1086

BTM-1086 is a potent anti-ulcer and gastric secretory inhibiting agent.

Product Specifications

CAS Number

72293-17-5

UNSPSC

12352005

Target

MAChR

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/1,5-Benzothiazepin-4_5H_-one,_2,3-dihydro-3-[_4-methyl-1-piperazinyl_methyl]-2-phenyl-,__2R,3S_-rel-.html

Solubility

10 mM in DMSO

Smiles

O=C1[C@H](CN2CCN(C)CC2)[C@H](C3=CC=CC=C3)SC4=CC=CC=C4N1

Molecular Formula

C21H25N3OS

Molecular Weight

367.51

References & Citations

[1]Eltze M, et al. Affinity profiles of BTM-1086 and BTM-1041 at muscarinic receptor subtypes and at H1- and alpha 1-receptors. Eur J Pharmacol. 1989 Nov 7;170 (3) :225-34.|[2]Hajimu Y, et al. Antiulcer Effect of (-) -cis-2, 3-Dihydro-3- (4-Methylpiperazinylmethyl) -2-Phenyl-1, 5-Benzothiazepin-4- (5H) -One Hydrochloride (BTM-1086) in Experimental Animals. Japan J Pharmacol. 41, 283-292 (1986) .