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JAK3-IN-7

JAK3-IN-7 is a potent and selective JAK3 inhibitor extracted from patent WO2011013785A1, has an IC50 of <0.01 μM.

Product Specifications

CAS Number

1263774-57-7

UNSPSC

12352005

Target

JAK

Type

Reference compound

Related Pathways

Epigenetics; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/1,6-Diazaspiro[3.5]nonane-1-propanenitrile,_3-methyl-_beta_-oxo-6-_7H-pyrrolo[2,3-d]pyrimidin-4-yl_-.html

Solubility

10 mM in DMSO

Smiles

N#CCC(N1CC(C)C12CN(C3=C4C(NC=C4)=NC=N3)CCC2)=O

Molecular Formula

C17H20N6O

Molecular Weight

324.38

References & Citations

[1]NOJI, Satoru, et al. NITROGEN-CONTAINING SPIRO-RING COMPOUND AND MEDICINAL USE OF SAME. WO2011013785A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

JAK3

Available Sizes

Frequently Asked Questions

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