Thrombin inhibitor 1
Product Specifications
UNSPSC Description
Thrombin inhibitor 1 is a potent thrombin inhibitor (Ki=0.66 nM, 2xaPTT=0.43 μM).
Target Antigen
Thrombin
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/2-Pyridineacetamide,_3-chloro-N-[_1R_-1-_3-chlorophenyl_ethyl]-6-[[2,2-difluoro-2-_1-oxido-2-pyridinyl_ethyl]amino]-,_1-oxide.html
Solubility
10 mM in DMSO
Smiles
C[C@H](C1=CC(Cl)=CC=C1)NC(CC2=C(Cl)C=CC(NCC(F)(C3=CC=CC=N3=O)F)=N2=O)=O
Molecular Weight
497.32
References & Citations
[1]Nantermet PG, et al. P2 pyridine N-oxide thrombin inhibitors: a novel peptidomimetic scaffold. Bioorg Med Chem Lett. 2005 Jun 2;15(11):2771-5.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-U00370/Thrombin-inhibitor-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-U00370/
Clinical Information
No Development Reported
CAS Number
855998-46-8
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