(4E) -SUN9221
(4E) -SUN9221 is a potent antagonist of α1-adrenergic receptor and 5-HT2 receptor, with antihypertensive and anti-platelet aggregation activities.
Product Specifications
UNSPSC
12352005
Target
5-HT Receptor; Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cardiovascular Disease; Endocrinology
Assay Protocol
https://www.medchemexpress.com/Pyrrolo[2,3-c]azepine-4,8_1H,5H_-dione,_1-[4-[4-_4-fluorobenzoyl_-1-piperidinyl]butyl]-6,7-dihydro-7-methyl-,_4-oxime,__4E_-.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=C/2C=CN1CCCCN3CCC(C(C4=CC=C(F)C=C4)=O)CC3)N(C)CCC2=N/O
Molecular Formula
C25H31FN4O3
Molecular Weight
454.54
References & Citations
[1]Mizuno A, et al. Synthesis and pharmacological evaluation of pyrroloazepine derivatives as potent antihypertensive agents with antiplatelet aggregation activity. Chem Pharm Bull (Tokyo) . 1999 Feb;47 (2) :246-56.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-U00367/4E-SUN9221-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-U00367/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
α-1 microglobulin
CAS Number
[222318-55-0]
Available Sizes
Curated Selection
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