YM158 (free base)
YM158 free base is a potent and selective LTD4 and TXA2 receptor antagonist with pA2 values of about 8.87 and 8.81, respectively.
Product Specifications
CAS Number
179102-65-9
Product Name Alternative
YM-57158
UNSPSC
12352005
Target
Leukotriene Receptor; Prostaglandin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Inflammation/Immunology; Endocrinology
Assay Protocol
https://www.medchemexpress.com/Benzamide,_N-[5-[3-[_4-chlorophenyl_sulfonyl]propyl]-2-_2H-tetrazol-5-ylmethoxy_phenyl]-3-[[4-_1,1-dimethylethyl_-2-thiazolyl]methoxy]-.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1=CC(CCCS(=O)(C2=CC=C(Cl)C=C2)=O)=CC=C1OCC3=NN=NN3)C4=CC=CC(OCC5=NC(C(C)(C)C)=CS5)=C4
Molecular Formula
C32H33ClN6O5S2
Molecular Weight
681.22
References & Citations
42
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1
Isoform
LTD4/CysLT1; TXA2/TP
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