MCHR1 antagonist 1
MCHR1 antagonist 1 is a selective antagonist of melanin concentrating hormone-1 (MCH1) receptor, with a Kb of 1 nM and a Ki of 4 nM at human MCH1, and may be used to reduce the body mass.
Product Specifications
CAS Number
391610-37-0
UNSPSC
12352005
Target
MCHR1 (GPR24)
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease; Endocrinology
Assay Protocol
https://www.medchemexpress.com/5-Pyrimidinecarboxylic_acid,_6-_3,4-difluorophenyl_-1,2,3,6-tetrahydro-4-_methoxymethyl_-2-oxo-1-[[[3-[4-_2-pyridinyl_-1-piperidinyl]propyl]amino]carbonyl]-,_methyl_ester.html
Solubility
10 mM in DMSO
Smiles
O=C(C(C(C1=CC=C(F)C(F)=C1)N2C(NCCCN3CCC(C4=NC=CC=C4)CC3)=O)=C(COC)NC2=O)OC
Molecular Formula
C28H33F2N5O5
Molecular Weight
557.59
References & Citations
[1]Selective melanin concentrating hormone-1 (MCH1) receptor antagonists and uses thereof. US 20030069261 A1
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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