CHK-IN-1
CHK-IN-1 is an inhibitor of CHK1 and CHK2, with anti-proliferative activities.
Product Specifications
CAS Number
1278405-51-8
UNSPSC
12352005
Target
Checkpoint Kinase (Chk)
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Thieno[2,3-d]pyridazine-7-carboxamide,_2-_3-fluorophenyl_-4-[_3S_-3-piperidinylamino]-,_hydrochloride.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=NN=C(N[C@@H]2CNCCC2)C3=C1SC(C4=CC=CC(F)=C4)=C3)N.[H]Cl
Molecular Formula
C18H19ClFN5OS
Molecular Weight
407.89
References & Citations
[1]Novel compounds and therapeutic use thereof for protein kinase inhibition. EP 2477496 A1
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Chk1; Chk2
Frequently Asked Questions
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