Aurora B inhibitor 1
Aurora B inhibitor 1 is an Aurora B (Aurora-1) inhibitor extracted from patent WO2007059299A1, compound 1-3, has a Ki value of <0.010 uM.
Product Specifications
CAS Number
937276-52-3
UNSPSC
12352005
Target
Aurora Kinase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Methanone,__5-chloro-2-fluorophenyl_[_3S_-3-[[4-_3-cyclopropyl-3-fluoro-1-azetidinyl_-6-[_5-methyl-1H-pyrazol-3-yl_amino]-2-pyrimidinyl]oxy]-1-pyrrolidinyl]-.html
Solubility
10 mM in DMSO
Smiles
FC1(C2CC2)CN(C3=NC(O[C@@H]4CN(C(C5=C(C=CC(Cl)=C5)F)=O)CC4)=NC(NC6=NNC(C)=C6)=C3)C1
Molecular Formula
C25H26ClF2N7O2
Molecular Weight
529.97
References & Citations
[1]FRAYSSE, Damien, et al. AMINOPYRIMIDINES USEFUL AS KINASE INHIBITORS. WO2007059299A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Aurora B
Available Sizes
Frequently Asked Questions
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