NEP-In-1
NEP-IN-1 is a neutral endopeptidase (NEP) inhibitor with IC50 of 2 nM for dNEP.
Product Specifications
CAS Number
[465527-94-0]
UNSPSC
12352005
Target
Neprilysin
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Cyclopentanepropanoic_acid,_1-[[[3-_4-chlorophenyl_propyl]amino]carbonyl]-_alpha_-_2-methoxyethyl_-.html
Solubility
10 mM in DMSO
Smiles
O=C(O)C(CC1(C(NCCCC2=CC=C(Cl)C=C2)=O)CCCC1)CCOC
Molecular Formula
C21H30ClNO4
Molecular Weight
395.92
References & Citations
[1]Pryde DC, et al. Novel selective inhibitors of neutral endopeptidase for the treatment of female sexual arousal disorder. Bioorg Med Chem. 2007 Jan 1;15 (1) :142-59.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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