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5-HT2A antagonist 1

5-HT2A antagonist 1 is a 5-HT2A antagonist extracted from patent US5728835A and JP 1007727. 5-HT2A antagonist 1 may be useful in treatment of gastrointestinal disorders circulatory disorders.

Product Specifications

CAS Number

204643-75-4

UNSPSC

12352005

Target

5-HT Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/Benzamide,_4-amino-N-[2-_4-benzoyl-1-piperidinyl_ethyl]-N-3-pyridinyl-.html

Solubility

10 mM in DMSO

Smiles

O=C(N(CCN1CCC(C(C2=CC=CC=C2)=O)CC1)C3=CC=CN=C3)C4=CC=C(N)C=C4

Molecular Formula

C26H28N4O2

Molecular Weight

428.53

References & Citations

[1]Aoki Tsuyoshi, et al. Substituted cyclic amine compound, production process thereof and pharmaceutical composition for circulatory organ use containing the same. US5728835A|[2]Preparation of 3-​pyridylamines as 5-​HT2 receptor antagonists for treatment of circulatory disorders

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

5-HT2 Receptor; α-1 microglobulin

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