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COX-2-IN-1

COX-2-IN-1 is potent and slective COX-2 inhibitor with an IC50 of 3.9 μM.

Product Specifications

CAS Number

787623-48-7

UNSPSC

12352005

Target

COX

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/1-_4-Sulfamylphenyl_-3-trifluoromethyl-5-_7-chloroindol-3-yl_-2-pyrazoline.html

Solubility

10 mM in DMSO

Smiles

O=S(C1=CC=C(N2N=C(C(F)(F)F)CC2C3=CNC4=C3C=CC=C4Cl)C=C1)(N)=O

Molecular Formula

C18H14ClF3N4O2S

Molecular Weight

442.84

References & Citations

[1]Reddy MV, et al. Design, synthesis, and biological evaluation of 1- (4-sulfamylphenyl) -3-trifluoromethyl-5-indolyl pyrazolines as cyclooxygenase-2 (COX-2) and lipoxygenase (LOX) inhibitors. Bioorg Med Chem. 2008 Apr 1;16 (7) :3907-16.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

COX-2

Frequently Asked Questions

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