CP-319340 (free base)

CP-319340 free base is a microsomal triglyceride transfer protein (MTP) inhibitor.

Product Specifications

CAS Number

[186390-35-2]

UNSPSC

12352005

Target

Microsomal Triglyceride Transfer Protein (MTP)

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/[1,1_acute_-Biphenyl]-2-carboxamide,_N-[1,2,3,4-tetrahydro-2-_1H-imidazol-2-ylmethyl_-6-isoquinolinyl]-4_acute_-_trifluoromethyl_-.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=CC=CC=C1C2=CC=C(C(F)(F)F)C=C2)NC3=CC4=C(CN(CC5=NC=CN5)CC4)C=C3

Molecular Formula

C27H23F3N4O

Molecular Weight

476.49

References & Citations

[1]Sugi, Kiyoshi, et al. Process for producing 4- (2-methylphenyl) benzotrifluoride. EP1700837A1.|[2]Ye, Jin, et al. Treating hepatitis C virus infection. US20080175864A1.|[3]Hussain MM, et al. Microsomal triglyceride transfer protein and its role in apoB-lipoprotein assembly. J Lipid Res. 2003 Jan;44 (1) :22-32.