4-Biphenylsulfonyl chloride
4-Biphenylsulfonyl chloride is a synthetic intermediate that participates in the sulfonamide formation reaction to synthesize antiproliferative compounds. The derivatives of 4-Biphenylsulfonyl chloride inhibit human head and neck squamous cell carcinoma (HNSCC) cells by increasing PTEN expression and inhibiting the PI3K/Akt/mTOR pathway. 4-Biphenylsulfonyl chloride can be used in the development of anticancer drugs for HNSCC[1].
Product Specifications
CAS Number
1623-93-4
UNSPSC
12352200
Hazard Statement
H314
Target
Drug Intermediate
Type
Biochemical Assay Reagents
Related Pathways
Others
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/4-biphenylsulfonyl-chloride.html
Purity
99.59
Solubility
DMSO : 200 mg/mL (ultrasonic)
Smiles
ClS(C1=CC=C(C2=CC=CC=C2)C=C1)(=O)=O
Molecular Formula
C12H9ClO2S
Molecular Weight
252.72
Precautions
H314
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Biochemical Assay Reagents
Clinical Information
No Development Reported
Frequently Asked Questions
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