SR121566A
Product Specifications
UNSPSC Description
SR121566A is a novel non-peptide Glycoprotein IIb/IIIa (GP IIb-IIIa) antagonist, which can inhibit ADP-, arachidonic acid- and collagen-induced human platelet aggregation with IC50s of 46±7.5, 56±6 and 42±3 nM, respectively.
Target Antigen
Integrin
Type
Reference compound
Related Pathways
Cytoskeleton
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/SR121566A.html
Solubility
10 mM in DMSO
Smiles
O=C(O)CN1CCC(N(C2=NC(C3=CC=C(C(N)=N)C=C3)=CS2)CCC(O)=O)CC1
Molecular Weight
431.51
References & Citations
[1]Herault JP, et al. Effect of SR121566A, a potent GP IIb-IIIa antagonist on platelet-mediated thrombin generation in vitro and in vivo. Thromb Haemost. 1998 Feb;79(2):383-8.|[2]Lorrain J, et al. Effects of SanOrg123781A, a synthetic hexadecasaccharide, in a mouse model of electrically induced carotid artery injury: synergism with the antiplatelet agent clopidogrel. J Pharmacol Exp Ther. 2004 Apr;309(1):235-40.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-U00235/SR121566A-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-U00235/
Clinical Information
No Development Reported
CAS Number
180144-61-0
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
27683121 3 x 1.0μg DNA
LRRC52 CRISPRa sgRNA lentivector (set of three targets)(Human)
Ask
View Details 
MBS7029104-01 0.02 mg
Recombinant Human Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 (RPN2)
Ask
View Details MBS7029104-02 0.1 mg
Recombinant Human Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 (RPN2)
Ask
View Details MBS7029104-03 5x 0.1 mg
Recombinant Human Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 (RPN2)
Ask
View Details