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BRL44385

BRL44385 is a potent and selective inhibitor of the replication of herpes simplex virus types 1 and 2 (HSV-1 and HSV2), varicella zoster virus (VZV) and Epstein-Barr virus (EBV) .

Product Specifications

CAS Number

[114778-60-8]

UNSPSC

12352005

Target

EBV; HSV

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/BRL44385.html

Solubility

10 mM in DMSO

Smiles

O=C1N=C(N)NC2=C1N=CN2OCCCO

Molecular Formula

C8H11N5O3

Molecular Weight

225.20

References & Citations

[1]M. R. Harnden, et al. Synthesis, oral bioavailability and in vivo activity of acetal derivatives of the selective antiherpesvirus agent 9- (3-hydroxypropoxy) guanine (SRL 44385) . Antiviral Chemistry & Chemotherapy (1994) 5 (3), 147-154.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

HSV-1; HSV-2

Curated Selection

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