WD2000-012547
Product Specifications
UNSPSC Description
WD2000-012547 is a selective poly(ADP-ribose)-polymerase (PARP-1) inhibitor with a pKi of 8.221.
Target Antigen
PARP
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage;Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/WD2000-012547.html
Solubility
10 mM in DMSO
Smiles
O=C(NCC1)C2=CC=CC3=C2C1=C(C4=CC=CC=C4)N3
Molecular Weight
262.31
References & Citations
[1]Fatima S, et al. Multiple receptor conformation docking, dock pose clustering and 3D QSAR studies on human poly(ADP-ribose) polymerase-1 (PARP-1) inhibitors. J Recept Signal Transduct Res. 2014 Oct;34(5):417-30.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-U00223/WD2000-012547-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-U00223/
Clinical Information
No Development Reported
CAS Number
283172-68-9
Curated Selection
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