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NNC45-0781

NNC45-0781 is a tissue-selective estrogen partial-agonist.

Product Specifications

CAS Number

207277-66-5

UNSPSC

12352005

Target

Estrogen Receptor/ERR

Type

Reference compound

Related Pathways

Vitamin D Related/Nuclear Receptor

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/NNC45-0781.html

Solubility

10 mM in DMSO

Smiles

OC1=CC=C([C@@H](C2=CC=C(OCCN3CCCC3)C=C2)[C@@H](C4=CC=CC=C4)CO5)C5=C1

Molecular Formula

C27H29NO3

Molecular Weight

415.52

References & Citations

[1]Bury PS, et al. Synthesis and pharmacological evaluation of novel cis-3,4-diaryl-hydroxychromanes as high affinity partial agonists for the estrogen receptor. Bioorg Med Chem. 2002 Jan;10 (1) :125-45.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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