Ro 41-3290
Ro 41-3290 is the desethylated derivative of Ro 41-3696, which is a nonbenzodiazepine partial agonist at the benzodiazepine receptor.
Product Specifications
CAS Number
143943-72-0
UNSPSC
12352005
Target
GABA Receptor
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Ro_41-3290.html
Solubility
10 mM in DMSO
Smiles
O[C@@H]1CN(C(C2=C3N(C(C(C4=CC=CC=C4)=C2)=O)CCC5=CC=C(Cl)C=C53)=O)CC1
Molecular Formula
C24H21ClN2O3
Molecular Weight
420.89
References & Citations
[1]Dingemanse J, et al. Pharmacokinetics and pharmacodynamics of Ro 41-3696, a novel nonbenzodiazepine hypnotic. J Clin Pharmacol. 1995 Aug;35 (8) :821-9.|[2]Dingemanse J, et al. Multiple-dose tolerability, pharmacodynamics, and pharmacokinetics of the quinolizinone hypnotic Ro 41-3696 in elderly subjects. Clin Neuropharmacol. 2001 Mar-Apr;24 (2) :82-90.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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