Dicirenone
Dicirenone (SC26304) inhibits the effects of Aldosterone on urinary K+:Na+ ratios and the binding of [3H]Aldosterone to renal cytoplasmic and nuclear receptors.
Product Specifications
CAS Number
41020-79-5
Product Name Alternative
SC26304
UNSPSC
12352005
Target
Mineralocorticoid Receptor
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/SC26304.html
Solubility
10 mM in DMSO
Smiles
C[C@@]12[C@@]3(OC(CC3)=O)CC[C@@]1([H])[C@@]4([H])[C@]([C@@]5(C(C[C@H]4C(OC(C)C)=O)=CC(CC5)=O)C)([H])CC2
Molecular Formula
C26H36O5
Molecular Weight
428.56
References & Citations
[1]Marver D, et al. Renal aldosterone receptors: studies with (3H) aldosterone and the anti-mineralocorticoid (3H) spirolactone (SC-26304) . Proc Natl Acad Sci U S A. 1974 Apr;71 (4) :1431-5.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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