Ro18-5362
Product Specifications
UNSPSC Description
Ro18-5362 is the less active proagent of Ro 18-5364. Even at concentrations as high as 0.1 mM Ro 18-5362 fails to affect significantly (H++K+)-ATPase activity and associated proton translocation.
Target Antigen
Others
Type
Reference compound
Related Pathways
Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/Ro18-5362.html
Solubility
10 mM in DMSO
Smiles
O=C1C(C)(C)C2=C(C=C3NC(SCC4=NC=CC(OC)=C4C)=NC3=C2)C1(C)C
Molecular Weight
395.52
References & Citations
[1]Sigrist-Nelson K, et al. Ro 18-5364, a potent new inhibitor of the gastric (H+ + K+)-ATPase. Eur J Biochem. 1987 Jul 15;166(2):453-9.|[2]Sigrist-Nelson K, et al. Gastric (H+ + K+)-ATPase: modulation of the inhibitory properties of the novel potent antisecretagogue Ro 18-5364 by sulfhydryl reagents and nucleotides. FEBS Lett. 1986 Mar 3;197(1-2):187-91.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-U00193/Ro18-5362-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-U00193/
Clinical Information
No Development Reported
CAS Number
101387-97-7
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6403563-01 0.1 mL
GM-CSF (Csf2, Granulocyte-macrophage Colony-stimulating Factor, Colony-stimulating Factor, CSF, Csfgm) (MaxLight 650)
Ask
View Details MBS6403563-02 5x 0.1 mL
GM-CSF (Csf2, Granulocyte-macrophage Colony-stimulating Factor, Colony-stimulating Factor, CSF, Csfgm) (MaxLight 650)
Ask
View Details MBS6312512-01 0.2 mL
Kcnj11, NT (Kcnj11, ATP-sensitive inward rectifier potassium channel 11, Inward rectifier K(+) channel Kir6.2, Potassium channel, inwardly rectifying subfamily J member 11) (APC)
Ask
View Details MBS6312512-02 5x 0.2 mL
Kcnj11, NT (Kcnj11, ATP-sensitive inward rectifier potassium channel 11, Inward rectifier K(+) channel Kir6.2, Potassium channel, inwardly rectifying subfamily J member 11) (APC)
Ask
View Details