NCX1022
NCX1022 is an NO-releasing derivative of Hydrocortisone, which is the most widely used anti-inflammatory agent for the treatment of skin inflammation.
Product Specifications
CAS Number
571186-50-0
UNSPSC
12352005
Target
NO Synthase
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/NCX1022.html
Solubility
10 mM in DMSO
Smiles
C[C@@]12[C@](CC[C@]2(O)C(COC(C3=CC=C(CON(=O)=O)C=C3)=O)=O)([H])[C@@]4([H])[C@]([C@@]5(C(CC4)=CC(CC5)=O)C)([H])[C@@H](O)C1
Molecular Formula
C29H35NO9
Molecular Weight
541.59
References & Citations
[1]Hyun E, et al. Anti-inflammatory effects of nitric oxide-releasing hydrocortisone NCX 1022, in a murine model of contact dermatitis. Br J Pharmacol. 2004 Nov;143 (5) :618-25.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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